Antibiofilm Formation Activities of Ethanol Extract of Curcuma domestica Val. Rhizome Against Multidrug-resistant Acinetobacter baumannii
نویسندگان
چکیده
Abstract.
 
 Multidrug resistance is still a major health problem worldwide. Biofilm formation was related to the of bacteria mechanism. Acinetobacter baumannii, one that cause nosocomial infections, given particular attention due its high prevalence resistance. The current study address observing antibacterial activity and antibiofilm Curcuma domestica rhizome extract against multidrug-resistant baumannii (MDR A.baumannii). macerated by ethanol 96%. Determination Minimum Inhibitory Concentration (MIC) carried out microdilution method. Antibiofilm analysis determined standard quantitative using crystal violet-stained assay. Ethanol C. possesses MDR A. with MIC value 250 µg/mL. Additionally, could inhibit biofilm A.baumannii, thus percentage formed only 23.7% significance different control after analyzed ANOVA post hoc test Tukey. According these results, revealed had potency in suppressing be utilized clinical application, especially A.baumannii infection.
 Keywords: Antibiofilm, antibacterial, domestica, multidrug-resistant, baumannii
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ژورنال
عنوان ژورنال: International Journal Of Science, Technology & Management
سال: 2023
ISSN: ['2722-4015']
DOI: https://doi.org/10.46729/ijstm.v4i4.883